<p>Topical 5 fluorouracil cream versus combined 5 flurorouracil and fractional erbium YAG laser for treatment of severe hypertrophic scars</p>

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Experimental Study of 5-fluorouracil Encapsulated Ethosomes Combined with CO2 Fractional Laser to Treat Hypertrophic Scar

OBJECTIVE This study is designed to explore permeability of ethosomes encapsulated with 5-florouracil (5-FU) mediated by CO2 fractional laser on hypertrophic scar tissues. Moreover, therapeutic and duration effect of CO2 fractional laser combined with 5-FU encapsulated ethosomes in rabbit ear hypertrophic scar model will be evaluated. METHODS The permeated amount of 5-FU and retention content...

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Treatment of Posttraumatic Scar with Ablative Fractional Erbium: YAG Laser

Scars following trauma [1] is a cause of concern for many a patient. Various modalities have been used for the treatment of scars over the years. Corticosteroids, dermabrasion, surgical revision, chemical peeling, silicone gel application, pressure therapy, and radiation have been used with varying results [2]. Ablative lasers such as the carbon dioxide (CO2), erbium: yttrium-aluminum-garnet (E...

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Efficacy of combination of fractional CO2 laser and tranexamic 5% gel in the treatment of melasma

Background and Aim: Melasma is a common disease affecting quality of life. Available treatments result in the gradual and partial clearance of melasma, and are accompanied with high risk of recurrence after discontinuing treatment. Tranexamic acid has been successfully evaluated in several studies. In addition, laser has been proposed as an enhanced drug delivery method. This study is designed ...

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Topical Tretinoin and 5-Fluorouracil in treatment of epidermal nevus

Background: Epidermal nevus is a common skin hamartoma. Its definite treatment is difficult and in most cases the disease has recurrence. Objective: Evaluation of topical tretinoin 0.05% and 5 Fluorouracil (5FU) 5% in the treatment of epidermal nevus. Patients and Methods: Fifteen patients with epidermal nevus referred to skin clinic in Razi Hospital in Tehran whose diagnoses were confirm...

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ژورنال

عنوان ژورنال: Clinical, Cosmetic and Investigational Dermatology

سال: 2019

ISSN: 1178-7015

DOI: 10.2147/ccid.s191137